Chromone

Chromone

SCHEMBL28860974

CCCC=O.O=c1ccoc2ccccc12

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.68
MAOA P21397 6/20 0.68
FTO Q9C0B1 2/20 0.68
ACHE P22303 1/20 0.41
GRM5 P41594 1/20 0.41
KDM4E B2RXH2 1/20 0.41
PTPN1 P18031 1/20 0.39
ALDH1A1 P00352 2/20 0.39
SIGMAR1 Q99720 2/20 0.38
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
KMT2A Q03164 1/20 0.37
ROCK2 O75116 1/20 0.36
ROCK1 Q13464 1/20 0.36
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chromone SCHEMBL27887886 0.83 MAOB (0.78) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL30075941 0.82 MAOA (1.00) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL6347379 0.82 MAOA (1.00) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL28268880 0.82 MAOA (1.00) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL29369932 0.82 MAOA (1.00) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL37994 0.82 MAOA (1.00) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL27464281 0.81 MAOB (0.64) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL28283851 0.81 MAOB (0.81) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL28958938 0.81 MAOB (0.88) MAOBMAOAFTOACHEGRM5
Chromone SCHEMBL1034108 0.80 MAOA (0.95) MAOBMAOAFTOACHEGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110506038-A PESTICIDAL COMPOUNDS BASF SE 2019-11-26 CN disclosed
CN-109476561-A Capsule comprising being used as the benzyl propargyl ether of nitrification inhibitor 巴斯夫欧洲公司 2019-03-15 CN disclosed
CN-108349941-A Prevent the pyridine compounds of plant pathogenic fungi 巴斯夫欧洲公司 2018-07-31 CN disclosed
CN-108290840-A Pyridine compounds as fungicide 巴斯夫欧洲公司 2018-07-17 CN disclosed
CN-108290839-A Pyridine compounds as fungicides 巴斯夫欧洲公司 2018-07-17 CN disclosed
CN-108137533-A Pyridine compounds for controlling phytopathogenic fungi 巴斯夫欧洲公司 2018-06-08 CN disclosed