SCHEMBL28861908

SCHEMBL28861908

CCC(C)Cc1cccc(CC(C)CC)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.42
CXCR4 P61073 1/20 0.36
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MCHR1 Q99705 1/20 0.36
TLR8 Q9NR97 2/20 0.36
TLR7 Q9NYK1 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
GPBAR1 Q8TDU6 1/20 0.35
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
HRH4 Q9H3N8 1/20 0.33
GRIN2D O15399 2/20 0.33
GRIN3B O60391 2/20 0.33
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
GRIN2B Q13224 2/20 0.33
GRIN2C Q14957 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23153083 0.86 MCHR1 (0.44) MCHR1TLR8TLR7NOS1NOS2
SCHEMBL24261163 0.83 KDM1A (0.40) MCHR1GPBAR1GRIN1GRIN2BTAAR1
SCHEMBL8256625 0.82 P2RX7 (0.41)
SCHEMBL24500673 0.79 MBOAT4 (0.41) NPSR1
SCHEMBL3625374 0.78 GABRA1 (0.44) KCNH2CXCR4SMN1; SMN2TLR7NPSR1
SCHEMBL7566490 0.77 GRIN2D (0.50) LMNATSHRSMN1; SMN2GRIN2DGRIN3B
SCHEMBL13272888 0.77 GRIN2D (0.50) LMNATSHRSMN1; SMN2GRIN2DGRIN3B
SCHEMBL12641681 0.76 KCNH2 (0.41) KCNH2CXCR4TSHRTLR7NPSR1
SCHEMBL24923647 0.75 CYP1A2 (0.49) TLR8TLR7GRIN1GRIN2B
SCHEMBL1129372 0.74 KCNH2 (0.39) KCNH2CXCR4NPSR1PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108383729-A A kind of purposes of organic base as catalyst carbonate synthesis dibasic ester 中国海洋石油集团有限公司 2018-08-10 CN disclosed