Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.33 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.33 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409550 | 0.89 | CYP3A4 (0.43) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL3962674 | 0.85 | MAPT (0.42) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL17960733 | 0.83 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2358955 | 0.82 | ALDH1A1 (0.60) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL21880057 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL5140277 | 0.81 | TSHR (0.40) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2733016 | 0.78 | CYP3A4 (0.39) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL28843514 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL3319342 | 0.77 | MAPT (0.44) | ALDH1A1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL11070215 | 0.77 | CYP3A4 (0.38) | ALDH1A1TSHRMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183170-A1 | 1,1-DISUBSTITUTED ETHYLENE PROCESS | OPTMED, INC. | 2023-06-15 | — | — | US | disclosed |
| US-11555011-B2 | 1,1-disubstituted ethylene process | H.B. FULLER COMPANY (US) | 2023-01-17 | — | — | US | disclosed |
| US-20200223790-A1 | IMPROVED 1,1-DISUBSTITUTED ETHYLENE PROCESS | OPTMED, INC. (US) | 2020-07-16 | — | — | US | disclosed |
| US-10597355-B2 | 1,1-disubstituted ethylene process | OPTMED, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| EP-2807138-B1 | PURIFICATION OF 1, 1-DISUBSTITUTED ETHYLENE COMPOUNDS | OPTMED INC (US) | 2019-10-16 | — | — | EP | disclosed |
| EP-2807142-B1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC (US) | 2019-09-04 | — | — | EP | disclosed |
| US-9540309-B2 | Methylidene malonate process | OPTMED, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9487468-B2 | Methylidene malonate process | OPTMED, INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20150203437-A1 | METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2015-07-23 | — | — | US | disclosed |
| US-20150183714-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. (US) | 2015-07-02 | — | — | US | disclosed |
| US-20100286439-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. | 2010-11-11 | — | — | US | disclosed |
| US-20100286438-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. | 2010-11-11 | — | — | US | disclosed |
| US-20100286433-A1 | METHYLIDENE MALONATE PROCESS | OPTMED, INC. | 2010-11-11 | — | — | US | disclosed |
| WO-2010129066-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010129068-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010129067-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-4160864-A | QUICK-SETTING | EASTMAN KODAK COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4160864-A | QUICK-SETTING | EASTMAN KODAK COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4160864-A | QUICK-SETTING | EASTMAN KODAK COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4056543-A | FROM A SUBSTITUTED NORBORNENE AND A HALOFORMATE, ALKYLLITHIUM AMIDE CATALYST | EASTMAN KODAK COMPANY (US) | 1977-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183170-A1 | 1,1-DISUBSTITUTED ETHYLENE PROCESS | ME1, MMAB, CA6 | ALDH1A1 751/4885TSHR 4763/4885MAPT 2275/4885 |
| US-20200223790-A1 | IMPROVED 1,1-DISUBSTITUTED ETHYLENE PROCESS | ME1, MMAB, CA6 | ALDH1A1 789/4885TSHR 4837/4885MAPT 2684/4885 |
| US-20100286439-A1 | METHYLIDENE MALONATE PROCESS | MPHOSPH6, ME1, MGAM | ALDH1A1 1618/4885TSHR 4548/4885MAPT 1890/4885 |
| US-20100286438-A1 | METHYLIDENE MALONATE PROCESS | MPHOSPH6, ME1, MGAM | ALDH1A1 1618/4885TSHR 4548/4885MAPT 1890/4885 |
| US-11555011-B2 | 1,1-disubstituted ethylene process | ME1, MAL2, CA6 | ALDH1A1 314/4885TSHR 4435/4885MAPT 3398/4885 |
| US-20100286433-A1 | METHYLIDENE MALONATE PROCESS | MMAB, ME1, MAL2 | ALDH1A1 1265/4885TSHR 4364/4885MAPT 2505/4885 |
| US-10597355-B2 | 1,1-disubstituted ethylene process | ME1, MMAB, CA6 | ALDH1A1 751/4885TSHR 4763/4885MAPT 2275/4885 |
| US-20150183714-A1 | METHYLIDENE MALONATE PROCESS | MPHOSPH6, ME1, MGAM | ALDH1A1 1618/4885TSHR 4548/4885MAPT 1890/4885 |
| US-20150203437-A1 | METHYLIDENE MALONATE PROCESS | MMAB, ME1, MAL2 | ALDH1A1 1265/4885TSHR 4364/4885MAPT 2505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.