SCHEMBL28864168

SCHEMBL28864168

CC(C)CC(=O)OCCCN

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38
HTR2C P28335 1/20 0.37
NAAA Q02083 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
PRKCA P17252 1/20 0.35
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
DPP4 P27487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23172143 0.87 MMP1 (0.41) CYP1A2MMP1MMP2MMP3MMP9
SCHEMBL18378814 0.82 MMP1 (0.46) MMP1MMP2MMP3MMP9MMP13
SCHEMBL2529024 0.81 MMP1 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL2529030 0.81 MMP1 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL1866046 0.81 ALDH1A1 (0.52) HTR2CNAAAALDH1A1TDP1MAPT
SCHEMBL18338892 0.81 MMP1 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL95383 0.81 ALDH1A1 (0.52) HTR2CNAAAALDH1A1TDP1MAPT
SCHEMBL2531293 0.79 NAAA (0.41) MMP1MMP2MMP3MMP9MMP13
SCHEMBL17891962 0.79 RARB (0.42) MMP1MMP2MMP3MMP9MMP13
SCHEMBL4198019 0.79 MMP1 (0.38) MMP1MMP2MMP3MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114901646-A Benzotriazine double oxide and pharmaceutical composition thereof 杭州瑞臻医药有限公司 2022-08-12 CN disclosed