SCHEMBL28864359

SCHEMBL28864359

C=CCc1ccc2cc3cc(B(O)O)ccc3cc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
GABRA1 P14867 4/20 0.47
GABRB2 P47870 4/20 0.47
MAPT P10636 3/20 0.47
CNR2 P34972 3/20 0.47
MEN1 O00255 2/20 0.47
GAA P10253 2/20 0.47
CNR1 P21554 2/20 0.47
KMT2A Q03164 2/20 0.47
PPARG P37231 2/20 0.47
PPARD Q03181 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH2 P05091 1/20 0.47
AKR1B1 P15121 1/20 0.47
HPGD P15428 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
XDH P47989 1/20 0.44
TNKS O95271 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28864355 0.97 ALDH1A1 (0.50) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL28864347 0.89 GABRA1 (0.46) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL7043823 0.84 XDH (0.54) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL11494827 0.84 XDH (0.54) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL198193 0.84 XDH (0.54) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL253471 0.84 XDH (0.54) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL7055734 0.84 XDH (0.54) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL3259762 0.80 XDH (0.58) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL4563164 0.78 XDH (0.48) ALDH1A1GABRA1GABRB2MAPTCNR2
SCHEMBL1116335 0.78 XDH (0.48) ALDH1A1GABRA1GABRB2MAPTCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197053-A Dihalogen cyclopropane derivative capable of releasing acid and preparation method and application thereof 中山大学 2022-10-18 CN claimed
CN-115197053-A Dihalogen cyclopropane derivative capable of releasing acid and preparation method and application thereof 中山大学 2022-10-18 CN disclosed