Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 4/20 | 0.59 |
| ▸ | CCR8 | P51685 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18177893 | 0.84 | ALDH1A1 (0.78) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL7646963 | 0.84 | KDM4E (0.75) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL14859627 | 0.82 | CCR8 (0.69) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL6499571 | 0.82 | ALDH1A1 (0.75) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL6496864 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL14859392 | 0.81 | KDM4E (0.63) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL3644401 | 0.81 | KDM4E (0.79) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL30302091 | 0.78 | KDM4E (0.75) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL13991979 | 0.78 | KDM4E (0.75) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL17276624 | 0.78 | KDM4E (0.75) | ALDH1A1KDM4ETDP1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108601769-A | Pyrazole compound and its preparation and application | 阿比德治疗公司 | 2018-09-28 | — | — | CN | disclosed |