Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | FAAH | O00519 | 12/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | MGLL | Q99685 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CCR8 | P51685 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3644401 | 0.89 | KDM4E (0.79) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7650588 | 0.88 | FAAH (0.68) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL30302091 | 0.87 | KDM4E (0.75) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL13991979 | 0.87 | KDM4E (0.75) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL17276624 | 0.87 | KDM4E (0.75) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL19049381 | 0.86 | ALDH1A1 (0.71) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL17276255 | 0.84 | MGLL (0.68) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL28864447 | 0.84 | ALDH1A1 (0.72) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL1943497 | 0.83 | HRH3 (0.75) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3593916 | 0.83 | FAAH (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1149214-C | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | ������������ʽ���� | 2004-05-12 | — | — | CN | disclosed |
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| CN-1293674-A | Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient | TORAY INDUSTRIES (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |