Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | GAA | P10253 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | FAAH | O00519 | 13/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MGLL | Q99685 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276624 | 1.00 | KDM4E (0.75) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3644401 | 0.89 | KDM4E (0.79) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL7646963 | 0.87 | KDM4E (0.75) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL13991979 | 0.87 | KDM4E (0.75) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL611401 | 0.84 | ALDH1A1 (0.68) | KDM4EALDH1A1LMNASMN1; SMN2FAAH | |
| SCHEMBL3355088 | 0.84 | FAAH (0.74) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3593916 | 0.83 | FAAH (1.00) | FAAH | |
| SCHEMBL17276255 | 0.82 | MGLL (0.68) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL12332155 | 0.80 | FAAH (0.70) | KDM4EALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL3642080 | 0.80 | FAAH (0.75) | KDM4EALDH1A1LMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116473965-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116473965-A | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-110678456-B | Pyrazole MAGL inhibitors | H.隆德贝克有限公司 | 2023-05-02 | — | — | CN | disclosed |