Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30670278 | 0.74 | — | — | |
| SCHEMBL31733896 | 0.71 | MAOA (0.32) | MAOAMAOBDPP4F2IDO1 | |
| SCHEMBL2180552 | 0.69 | MAOA (0.37) | MAOAMAOB | |
| Methane SCHEMBL29222891 | 0.68 | MAOA (0.36) | MAOAMAOB | |
| SCHEMBL27366612 | 0.64 | MAOB (0.37) | MAOAMAOBIDO1 | |
| SCHEMBL28481200 | 0.64 | MEN1 (0.37) | — | |
| SCHEMBL28703048 | 0.64 | — | — | |
| SCHEMBL28506792 | 0.63 | LMNA (0.35) | F2 | |
| SCHEMBL24445050 | 0.61 | MAOA (0.39) | MAOAMAOB | |
| SCHEMBL28218964 | 0.61 | MAOA (0.39) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473478-A | TBK/IKK inhibitor compounds and uses thereof | 默克专利有限公司 | 2018-08-31 | — | — | CN | disclosed |