Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.39 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214420 | 0.81 | MAOA (0.36) | MAOAMAOBKDM1AOPRL1HSD11B1 | |
| SCHEMBL31198169 | 0.79 | CALM1 (0.34) | MAOAMAOBOPRL1HSD11B1OPRM1 | |
| SCHEMBL24445050 | 0.77 | MAOA (0.39) | MAOAMAOBKDM1ABACE1LMNA | |
| SCHEMBL28218904 | 0.74 | HSD11B1 (0.35) | MAOAMAOBHSD11B1LMNAHTT | |
| SCHEMBL10587681 | 0.70 | LMNA (0.38) | MAOAMAOBKDM1AOPRL1HSD11B1 | |
| SCHEMBL18840049 | 0.66 | KDM1A (0.37) | MAOAMAOBKDM1AOPRL1HSD11B1 | |
| SCHEMBL9193910 | 0.66 | MAOA (0.41) | MAOAMAOBKDM1AOPRL1HSD11B1 | |
| SCHEMBL4085180 | 0.63 | GBA1 (0.38) | MAOAMAOBKDM1AHSD11B1LMNA | |
| SCHEMBL23343753 | 0.61 | OPRL1 (0.65) | MAOAMAOBOPRL1OPRM1OPRD1 | |
| SCHEMBL30915521 | 0.61 | MAOA (0.36) | MAOAMAOBKDM1ABACE1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973727-B | M-disubstituted phenol compound, preparation method and anti-tubercle bacillus application thereof | 中山大学 | 2020-04-17 | — | — | CN | disclosed |
| CN-107973727-A | Between disubstituted benzenes phenolic compounds and preparation method thereof and anti-tubercle bacillus application | 中山大学 | 2018-05-01 | — | — | CN | disclosed |