SCHEMBL28864615

SCHEMBL28864615

C#CC1CN(CC(=O)OC(=O)C(F)(F)F)CCO1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIT P10721 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28864606 0.80 PDK1 (0.38)
SCHEMBL28864623 0.80 PDK1 (0.38)
Trifluoroacetic Acid SCHEMBL28864617 0.80 HSD17B10 (0.39)
SCHEMBL28864583 0.79 PLA2G10 (0.33)
SCHEMBL28864580 0.76 HSD17B10 (0.46)
SCHEMBL6284937 0.74 KDM4E (0.47)
SCHEMBL28864655 0.74
SCHEMBL20838985 0.70 HRH2 (0.35) KIT
SCHEMBL20838978 0.70 HRH2 (0.35) KIT
SCHEMBL28864674 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115244047-A Indazole derivative and application thereof in medicine 四川海思科制药有限公司 2022-10-25 CN disclosed