Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28864617 | 0.91 | HSD17B10 (0.39) | HSD17B10 | |
| SCHEMBL28864583 | 0.78 | PLA2G10 (0.33) | — | |
| SCHEMBL12331034 | 0.77 | HSD17B10 (0.50) | HSD17B10GLAPDK1KDM4EALOX15 | |
| SCHEMBL28864615 | 0.76 | KIT (0.30) | — | |
| SCHEMBL28864611 | 0.74 | HSD17B10 (0.50) | HSD17B10GLAPDK1KDM4E | |
| SCHEMBL715037 | 0.74 | HSD17B10 (0.50) | HSD17B10GLAPDK1KDM4E | |
| SCHEMBL28864627 | 0.74 | HSD17B10 (0.50) | HSD17B10GLAPDK1KDM4E | |
| SCHEMBL15920658 | 0.74 | PDK1 (0.37) | PDK1 | |
| SCHEMBL28864592 | 0.72 | HSD17B10 (0.48) | HSD17B10GLAPDK1KDM4E | |
| SCHEMBL169122 | 0.72 | HSD17B10 (0.48) | HSD17B10GLAPDK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244047-A | Indazole derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-10-25 | — | — | CN | disclosed |