Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163741 | 0.86 | MET (0.50) | METPDGFRBPDGFRA | |
| SCHEMBL28680573 | 0.86 | MET (0.50) | METPDGFRBPDGFRA | |
| SCHEMBL29870023 | 0.86 | MET (0.50) | METPDGFRBPDGFRA | |
| SCHEMBL14872903 | 0.79 | USP2 (0.43) | TP53ALDH1A1LMNAUSP2TSHR | |
| SCHEMBL20675604 | 0.76 | ALDH1A1 (0.50) | METPOLBTP53ATAD2ALDH1A1 | |
| SCHEMBL10285463 | 0.76 | ATM (0.48) | ALDH1A1TSHR | |
| SCHEMBL28864697 | 0.75 | MET (0.44) | METPOLBTP53LMNA | |
| SCHEMBL14870378 | 0.75 | EGFR (0.42) | ALDH1A1LMNAUSP2TSHR | |
| SCHEMBL17718345 | 0.75 | EGFR (0.42) | ALDH1A1LMNAUSP2TSHR | |
| SCHEMBL29869723 | 0.73 | ALDH1A1 (0.47) | METPOLBTP53ATAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |