Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445436 | 0.85 | LMNA (0.40) | METMAPTLMNATP53 | |
| SCHEMBL28864685 | 0.75 | MET (0.47) | METLMNATP53POLB | |
| SCHEMBL20666233 | 0.75 | MAPT (0.54) | METACVR1KDM4EMAPTLMNA | |
| SCHEMBL15445435 | 0.73 | LMNA (0.39) | LMNATP53 | |
| SCHEMBL2730026 | 0.73 | LMNA (0.39) | LMNATP53 | |
| SCHEMBL27988627 | 0.72 | MAPT (0.50) | METKDM4EMAPTLMNACYP1A2 | |
| SCHEMBL28864799 | 0.72 | MAPT (0.50) | METACVR1KDM4EMAPTLMNA | |
| SCHEMBL29869791 | 0.72 | MAPT (0.50) | METACVR1KDM4EMAPTLMNA | |
| SCHEMBL1163741 | 0.72 | MET (0.50) | MET | |
| SCHEMBL28680573 | 0.72 | MET (0.50) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312009-B | Quinoline compound, preparation method, intermediate, pharmaceutical composition and application thereof | 上海医药集团股份有限公司 | 2022-09-20 | — | — | CN | disclosed |