Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288924 | 0.80 | GPR119 (0.33) | GPR119 | |
| SCHEMBL298803 | 0.75 | PIK3CD (0.39) | GPR119 | |
| SCHEMBL1768128 | 0.75 | PIK3CD (0.39) | GPR119 | |
| SCHEMBL288648 | 0.75 | PIK3CD (0.39) | GPR119 | |
| SCHEMBL761207 | 0.74 | PIK3CD (0.35) | GPR119 | |
| SCHEMBL288925 | 0.73 | GPR119 (0.46) | GPR119 | |
| SCHEMBL1768278 | 0.72 | GPR119 (0.32) | GPR119 | |
| SCHEMBL290305 | 0.69 | GPR119 (0.45) | GPR119 | |
| SCHEMBL298608 | 0.68 | CNR2 (0.32) | GPR119 | |
| SCHEMBL761206 | 0.67 | PIK3CD (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427450-A1 | GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| EP-2427448-A1 | Gpr 119 modulators | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128414-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128425-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |