Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288924 | 0.85 | GPR119 (0.33) | GPR119 | |
| SCHEMBL288948 | 0.81 | GPR119 (0.65) | GPR119CYP2C9 | |
| SCHEMBL1445594 | 0.80 | GPR119 (0.40) | GPR119CYP2C9 | |
| SCHEMBL6066337 | 0.80 | GPR119 (0.58) | GPR119CYP2C9 | |
| SCHEMBL10120902 | 0.76 | GPR119 (0.67) | GPR119 | |
| SCHEMBL10106329 | 0.76 | GPR119 (0.67) | GPR119 | |
| SCHEMBL12277411 | 0.73 | GPR119 (0.67) | GPR119CYP2C9 | |
| SCHEMBL12277466 | 0.73 | GPR119 (0.67) | GPR119CYP2C9 | |
| SCHEMBL12236456 | 0.73 | GPR119 (0.69) | GPR119CYP2C9 | |
| SCHEMBL6456096 | 0.73 | GPR119 (0.54) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504342-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | Pfizer Inc. (US) | 2012-10-03 | — | — | EP | disclosed |
| EP-2480551-A1 | GPR 119 MODULATORS | Pfizer Inc. (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-2427448-A1 | Gpr 119 modulators | Pfizer Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2011061679-A1 | IMIDAZO-PYRAZOLES AS GPR119 INHIBITORS | PFIZER INC. (US) | 2011-05-26 | — | — | WO | disclosed |
| WO-2011036576-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2011-03-31 | — | — | WO | disclosed |
| WO-2010128414-A1 | GPR 119 MODULATORS | PFIZER INC. (US) | 2010-11-11 | — | — | WO | disclosed |