Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249602 | 0.88 | MEN1 (0.58) | KMT2AMAPTMEN1 | |
| SCHEMBL28681789 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9221084 | 0.83 | KMT2A (0.47) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL21252722 | 0.81 | KMT2A (0.49) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL23318972 | 0.80 | HIF1A (0.66) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11257064 | 0.79 | CYP3A4 (0.45) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11430447 | 0.79 | KMT2A (0.44) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL498198 | 0.79 | MAPT (0.44) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2500899 | 0.79 | MAPT (0.46) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11418687 | 0.79 | KMT2A (0.49) | ALDH1A1KMT2AMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022270478-A1 | ANTIVIRAL AGENT | 国立大学法人北海道大学 | 2022-12-29 | — | — | WO | disclosed |
| US-8604235-B2 | Production of substituted phenylene aromatic diesters and compositions | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | W. R. GRACE & CO.-CONN. | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204506-A1 | Production of Substituted Phenylene Aromatic Diesters and Compositions | PAH, DDC, DDT | ALDH1A1 240/4885KMT2A 1611/4885MAPT 2384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.