Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | BLM | P54132 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | THPO | P40225 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281120 | 0.86 | LMNA (0.55) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL11281093 | 0.85 | ADRB2 (0.56) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| SCHEMBL11278863 | 0.84 | ALDH1A1 (0.59) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| SCHEMBL11257064 | 0.83 | CYP3A4 (0.45) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| SCHEMBL23318966 | 0.83 | HIF1A (0.72) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| Dipivefrin SCHEMBL11358316 | 0.82 | HIF1A (0.78) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL9348676 | 0.82 | ADRB2 (0.59) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| SCHEMBL23337952 | 0.82 | HIF1A (0.71) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| SCHEMBL20142145 | 0.82 | HIF1A (0.71) | HIF1ACYP3A4ALDH1A1LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL9344932 | 0.81 | ADRB2 (0.58) | HIF1ACYP3A4ALDH1A1LMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128511-A1 | PRODRUG COMPOSITIONS AND METHODS OF TREATMENT | AQUESTIVE THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | US | disclosed |
| WO-2021087359-A1 | PRODRUG COMPOSITIONS AND METHODS OF TREATMENT | AQUESTIVE THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128511-A1 | PRODRUG COMPOSITIONS AND METHODS OF TREATMENT | ADRA2C, ADRB3, ADRA2B | HIF1A 2267/4885CYP3A4 127/4885ALDH1A1 559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.