Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704281 | 0.83 | LIPE (0.40) | MAPTLMNAHTTKDM4EHPGD | |
| SCHEMBL29994408 | 0.83 | LIPE (0.40) | MAPTLMNAHTTKDM4EHPGD | |
| SCHEMBL29994897 | 0.82 | KDM4E (0.52) | MAPTLMNAHTTKDM4EHPGD | |
| SCHEMBL23704307 | 0.82 | KDM4E (0.52) | MAPTLMNAHTTKDM4EHPGD | |
| SCHEMBL29994010 | 0.81 | GAA (0.35) | MAPTLMNAHTTKDM4EHPGD | |
| SCHEMBL23704265 | 0.81 | GAA (0.35) | MAPTLMNAHTTKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL23704353 | 0.80 | GAA (0.36) | MAPTLMNAHTTKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL29994246 | 0.80 | GAA (0.36) | MAPTLMNAHTTKDM4EHPGD | |
| SCHEMBL23704277 | 0.80 | MAPT (0.43) | MAPTLMNAHTTKDM4EHPGD | |
| SCHEMBL23707374 | 0.77 | ERCC1 (0.41) | MAPTLMNAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052860-B | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-115052860-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2022-09-13 | — | — | CN | disclosed |