SCHEMBL23704281

SCHEMBL23704281

CCOC(=O)Cc1ccc2[nH]c(C3CCOCC3)c(C)c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LIPE Q05469 1/20 0.40
▸ HCRTR1 O43613 1/20 0.39
▸ KDM4E B2RXH2 6/20 0.38
▸ KMT2A Q03164 5/20 0.38
▸ MEN1 O00255 4/20 0.38
▸ L3MBTL1 Q9Y468 2/20 0.38
▸ MAPT P10636 5/20 0.38
▸ LMNA P02545 3/20 0.38
▸ HTT P42858 2/20 0.37
▸ GAA P10253 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.37
▸ HPGD P15428 3/20 0.37
▸ HSD17B10 Q99714 2/20 0.37
▸ AKT1 P31749 1/20 0.37
▸ NPC1 O15118 3/20 0.37
▸ RAB9A P51151 3/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ MAPKAPK2 P49137 1/20 0.37
▸ PKM P14618 1/20 0.36
▸ NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29994408 1.00 LIPE (0.40) LIPEHCRTR1KDM4EKMT2AMEN1
SCHEMBL23704307 0.86 KDM4E (0.52) KDM4EKMT2AMEN1MAPTLMNA
SCHEMBL29994897 0.86 KDM4E (0.52) KDM4EKMT2AMEN1MAPTLMNA
SCHEMBL28864937 0.83 MAPT (0.39) HCRTR1KDM4EKMT2AMEN1L3MBTL1
SCHEMBL23704277 0.80 MAPT (0.43) KDM4EKMT2AMEN1L3MBTL1MAPT
SCHEMBL23704265 0.79 GAA (0.35) KDM4EKMT2AMEN1MAPTLMNA
SCHEMBL29994010 0.79 GAA (0.35) KDM4EKMT2AMEN1MAPTLMNA
Hydrochloric Acid SCHEMBL23704353 0.78 GAA (0.36) KDM4EKMT2AMEN1MAPTLMNA
Hydrochloric Acid SCHEMBL29994246 0.78 GAA (0.36) KDM4EKMT2AMEN1MAPTLMNA
SCHEMBL23707374 0.77 ERCC1 (0.41) KDM4EKMT2AMEN1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115052860-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-06-21 — — CN disclosed
US-20230116201-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-04-13 — — US disclosed
EP-4097084-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2022-12-07 — — EP disclosed
CN-115052860-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-09-13 — — CN disclosed
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 — — WO disclosed
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230116201-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 LIPE 4541/4885HCRTR1 3591/4885KDM4E 1893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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