SCHEMBL2886545

SCHEMBL2886545

FC(F)(F)c1ccc2[c]s[c]c2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 1/20 0.41
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CES2 O00748 2/20 0.34
EPHX2 P34913 1/20 0.34
SCN4A P35499 1/20 0.34
CYBB P04839 1/20 0.33
NOX3 Q9HBY0 1/20 0.33
NOX4 Q9NPH5 1/20 0.33
NOX1 Q9Y5S8 1/20 0.33
PNMT P11086 3/20 0.33
KIF11 P52732 3/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 2/20 0.32
PKM P14618 1/20 0.32
BACE1 P56817 1/20 0.32
GPR3 P46089 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
METAP2 P50579 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5543631 0.71 PTPN5 (0.38) PTPN5TSHRMAPK1CES2EPHX2
SCHEMBL5542365 0.71 PTPN5 (0.38) PTPN5TSHRMAPK1CES2EPHX2
SCHEMBL5544606 0.67 KIF11 (0.41) PTPN5EPHX2KIF11KDM4E
SCHEMBL5535793 0.67 KIF11 (0.39) PTPN5EPHX2KIF11HSD17B10
SCHEMBL5538925 0.65 EPHX2 (0.39) PTPN5TSHRMAPK1CES2EPHX2
SCHEMBL7164162 0.64 BACE1 (0.39) PTPN5TSHRMAPK1CES2EPHX2
SCHEMBL5540059 0.63 EPHX2 (0.40) PTPN5EPHX2SCN4AKIF11KDM4E
SCHEMBL5540051 0.63 EPHX2 (0.37) PTPN5EPHX2SCN4AKIF11KDM4E
SCHEMBL63468 0.63 ALDH1A1 (0.67) TSHRCES2EPHX2KIF11ALDH1A1
SCHEMBL7588186 0.63 BACE1 (0.56) PTPN5TSHRMAPK1CES2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1728256-B1 CROSSLINKED SELF-DOPING TYPE ELECTRICALLY CONDUCTING POLYMER, PRODUCTION PROCESS THEREOF, PRODUCT COATED WITH THE POLYMER AND ELECTRONIC DEVICE SHOWA DENKO KK (JP) 2015-05-13 EP disclosed
US-7857999-B2 Crosslinked self-doping type electrically conducting polymer, production process thereof, product coated with the polymer and electronic device SHOWA DENKO K.K. (JP) 2010-12-28 US disclosed
EP-2207185-A1 Crosslinked self-doping type electrically conducting polymer, production process thereof, product coated with the polymer and electronic device SHOWA DENKO KABUSHIKI KAISHA (JP) 2010-07-14 EP disclosed
US-20100103590-A1 SOLID ELECTROLYTIC CAPACITOR AND PRODUCTION METHOD THEREOF SHOWA DENKO K.K. (JP) 2010-04-29 US disclosed
US-20100026177-A1 CROSSLINKED SELF-DOPING TYPE ELECTRICALLY CONDUCTING POLYMER, PRODUCTION PROCESS THEREOF, PRODUCT COATED WITH THE POLYMER AND ELECTRONIC DEVICE SHOWA DENKO K.K. (JP) 2010-02-04 US disclosed
US-7638071-B2 Crosslinked self-doping type electrically conducting polymer, production process thereof, product coated with the polymer and electronic device SHOWA DENKO K.K. (JP) 2009-12-29 US disclosed
US-20070194285-A1 Crosslinked Self-Doping Type Electrically Conducting Polymer, Production Process Thereof, Product Coated With The Polymer And Electronic Device SHOWA DENKO K.K. (JP) 2007-08-23 US disclosed
WO-2007001076-A1 SOLID ELECTROLYTIC CAPACITOR AND PRODUCTION METHOD THEREOF SHOWA DENKO K.K. (JP) 2007-01-04 WO disclosed
EP-1728256-A1 CROSSLINKED SELF-DOPING TYPE ELECTRICALLY CONDUCTING POLYMER, PRODUCTION PROCESS THEREOF, PRODUCT COATED WITH THE POLYMER AND ELECTRONIC DEVICE Showa Denko K.K. (JP) 2006-12-06 EP disclosed
WO-2005091309-A1 CROSSLINKED SELF-DOPING TYPE ELECTRICALLY CONDUCTING POLYMER, PRODUCTION PROCESS THEREOF, PRODUCT COATED WITH THE POLYMER AND ELECTRONIC DEVICE SHOWA DENKO K.K. (JP) 2005-09-29 WO disclosed