Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486500 | 0.86 | PARP1 (0.40) | ESR2ESR1PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL27434748 | 0.83 | — | — | |
| SCHEMBL27475492 | 0.83 | FERMT2 (0.36) | PDGFRBPDGFRAMEN1KMT2AKDM4E | |
| SCHEMBL28248094 | 0.83 | CYP1A2 (0.42) | TLR8ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28165317 | 0.80 | HTR1A (0.43) | TLR8ALDH1A1KDM4EHPGDEGFR | |
| SCHEMBL28115761 | 0.79 | KDM4E (0.42) | ALDH1A1PDE10AKDM4EHPGDHSD17B10 | |
| SCHEMBL28160791 | 0.70 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDEGFRNQO1 | |
| SCHEMBL27903036 | 0.69 | CA12 (0.44) | ESR2ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL11062749 | 0.68 | CYP3A4 (0.43) | TLR8ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11070136 | 0.68 | FERMT2 (0.37) | ALDH1A1KDM4EHPGDNQO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623590-A | A kind of Fourth Ring quinolinone alkaloid derivant and its preparation method and application | 中国海洋大学 | 2018-10-09 | — | — | CN | disclosed |