Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886568 | 1.00 | L3MBTL1 (0.62) | L3MBTL1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL2882114 | 0.94 | L3MBTL1 (0.63) | L3MBTL1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL2882111 | 0.94 | L3MBTL1 (0.63) | L3MBTL1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL12174660 | 0.87 | L3MBTL1 (0.62) | L3MBTL1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL2397228 | 0.84 | L3MBTL1 (0.69) | L3MBTL1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6306108 | 0.84 | MTNR1A (0.63) | L3MBTL1MTNR1AMTNR1BTDP1 | |
| SCHEMBL31326036 | 0.83 | KMT2A (0.70) | L3MBTL1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL9393589 | 0.83 | L3MBTL1 (0.60) | L3MBTL1MTNR1AMTNR1BKMT2A | |
| SCHEMBL27685616 | 0.82 | L3MBTL1 (0.52) | L3MBTL1MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL12158740 | 0.82 | L3MBTL1 (0.62) | L3MBTL1MTNR1AMTNR1BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | MSD K.K. (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2042478-A1 | METHOD FOR PRODUCING -DIARYL ELECTRON-WITHDRAWING GROUP SUBSTITUTED COMPOUND | Japan Science and Technology Agency (JP) | 2009-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | BMP6, GPR6, ACSL6 | L3MBTL1 556/4885MTNR1A 2869/4885MTNR1B 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.