SCHEMBL28865758

SCHEMBL28865758

CN(C)CCCN(CCCN(C)C)C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.50
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
ADH1A P07327 5/20 0.37
ADH1C P00326 4/20 0.37
PKM P14618 1/20 0.34
ADH1B P00325 1/20 0.33
LTA4H P09960 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
FAAH O00519 1/20 0.33
PHGDH O43175 1/20 0.33
MGLL Q99685 1/20 0.33
DNM1 Q05193 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9424888 0.82 SIGMAR1 (0.50) SIGMAR1ALDH1A1TSHRADH1AADH1C
SCHEMBL13744824 0.80 ALDH1A1 (0.36) SIGMAR1ALDH1A1TSHRDNM1
SCHEMBL7649241 0.79 SIGMAR1 (0.44) SIGMAR1ALDH1A1TSHRADH1AADH1C
SCHEMBL627799 0.79 ADH1A (0.45) ADH1AADH1CDRD2DRD4DRD3
SCHEMBL6062901 0.77 ADH1A (0.44) SIGMAR1ADH1AADH1CDRD2DRD4
Bromide SCHEMBL28388955 0.77 ADH1A (0.44) ADH1AADH1CDRD2DRD4DRD3
Fluoride SCHEMBL9620624 0.77 ADH1A (0.44) ADH1AADH1CDRD2DRD4DRD3
SCHEMBL9551192 0.77 ADH1A (0.44) SIGMAR1ADH1AADH1CDRD2DRD4
SCHEMBL22749520 0.77 MAPT (0.42) SIGMAR1ALDH1A1TSHRADH1AADH1C
SCHEMBL517191 0.76 ADH1A (0.43) ADH1AADH1CDRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215751-B Preparation and application of tertiary amine catalyst and organic metal-tertiary amine complex catalyst 万华化学集团股份有限公司 2024-02-02 CN claimed
CN-115215751-A Tertiary amine catalyst and preparation and application of organic metal-tertiary amine complex catalyst 万华化学集团股份有限公司 2022-10-21 CN claimed
CN-115215751-B Preparation and application of tertiary amine catalyst and organic metal-tertiary amine complex catalyst 万华化学集团股份有限公司 2024-02-02 CN disclosed
CN-115215751-A Tertiary amine catalyst and preparation and application of organic metal-tertiary amine complex catalyst 万华化学集团股份有限公司 2022-10-21 CN disclosed