Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 4/20 | 0.61 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.61 |
| ▸ | CDK2 | P24941 | 3/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.61 |
| ▸ | RXRB | P28702 | 1/20 | 0.61 |
| ▸ | RXRG | P48443 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28865736 | 0.92 | CCNE1 (0.57) | KARS1CCNE1CDK2RXRARXRB | |
| SCHEMBL28865731 | 0.92 | TDP1 (0.61) | KARS1CCNE1CDK2RXRARXRB | |
| SCHEMBL11768691 | 0.87 | KARS1 (0.74) | KARS1CCNE1CDK2RXRARXRB | |
| SCHEMBL11479687 | 0.79 | KARS1 (0.73) | KARS1CCNE1CDK2RXRARXRB | |
| SCHEMBL11696149 | 0.79 | TDP1 (0.75) | KARS1CCNE1CDK2RXRARXRB | |
| SCHEMBL11695232 | 0.79 | KARS1 (0.68) | KARS1CCNE1CDK2RXRARXRB | |
| SCHEMBL29437389 | 0.78 | KARS1 (0.63) | KARS1CCNE1CDK2RXRARXRB | |
| SCHEMBL2675571 | 0.78 | CYP3A4 (0.78) | KARS1CCNE1CDK2RXRARXRB | |
| SCHEMBL11697145 | 0.78 | KARS1 (0.70) | KARS1CCNE1CDK2RXRARXRB | |
| Dehydroabietic Acid SCHEMBL2603437 | 0.78 | KARS1 (1.00) | KARS1CCNE1CDK2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073361-A | Rosin diterpenoid compound and preparation method and application thereof | 广东药科大学 | 2022-09-20 | — | — | CN | disclosed |