SCHEMBL28865796

SCHEMBL28865796

Cc1cc(C)cc(-c2ccc3c(CC(F)C(C(F)F)C(F)(F)F)cccc3n2)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28865795 0.88 KMT2A (0.34) LMNA
SCHEMBL10319231 0.79 DHODH (0.40) LMNA
SCHEMBL17666817 0.78 AR (0.33) ARLMNA
SCHEMBL17680368 0.77 AR (0.32) ARLMNA
SCHEMBL20809038 0.76 LMNA (0.37) ARLMNA
SCHEMBL17666818 0.76 CDK9 (0.35) ARLMNA
SCHEMBL13731884 0.75 GRM2 (0.35) ARLMNA
SCHEMBL16362419 0.74 DHODH (0.36) LMNA
SCHEMBL24513499 0.73 TACR3 (0.36) LMNA
SCHEMBL17666807 0.72 AR (0.54) ARLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115304647-A Organic electroluminescent material and device 环球展览公司 2022-11-08 CN disclosed
CN-115216291-A Organic electroluminescent material and device 环球展览公司 2022-10-21 CN disclosed