Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 9/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19440644 | 0.80 | SYK (0.37) | PABPC1SYKCREBBPBRD4POLB | |
| SCHEMBL21494778 | 0.75 | MEN1 (0.40) | SYKCREBBPBRD4POLBMAPT | |
| SCHEMBL544070 | 0.75 | MEN1 (0.41) | PABPC1CREBBPBRD4POLBALDH1A1 | |
| SCHEMBL10933576 | 0.72 | CA12 (0.49) | SYKALDH1A1TSHR | |
| SCHEMBL27467128 | 0.72 | ADORA2A (0.37) | POLBTSHRFYN | |
| SCHEMBL15808420 | 0.71 | IMPDH2 (0.40) | CREBBPBRD4ALDH1A1MAPTTSHR | |
| SCHEMBL29506423 | 0.70 | PABPC1 (0.59) | PABPC1POLBALDH1A1MAPTTSHR | |
| SCHEMBL15453221 | 0.70 | PABPC1 (0.59) | PABPC1POLBALDH1A1MAPTTSHR | |
| SCHEMBL16775248 | 0.70 | CREBBP (0.38) | CREBBPBRD4POLBALDH1A1MAPT | |
| SCHEMBL7946910 | 0.70 | CYP2A6 (0.42) | CREBBPBRD4POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699038-A | Loop coil heptane salicylamide and related compound as Rock inhibitor | 百时美施贵宝公司 | 2018-10-23 | — | — | CN | disclosed |