Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | RB1 | P06400 | 2/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27700723 | 0.89 | RB1 (0.52) | NR2E1HTR2AHTR2CKDM4EHTR5A | |
| SCHEMBL7066276 | 0.81 | NR2E1 (0.63) | NR2E1HTR2AHTR2CHPGDHSD17B10 | |
| SCHEMBL2515919 | 0.77 | NR2E1 (0.67) | NR2E1HTR2AHTR2CHPGDHSD17B10 | |
| SCHEMBL4288282 | 0.77 | NR2E1 (0.67) | NR2E1HTR2AHTR2CHPGDHSD17B10 | |
| SCHEMBL833503 | 0.74 | NR2E1 (1.00) | NR2E1HTR2AHTR2CHPGDHSD17B10 | |
| SCHEMBL21900686 | 0.74 | NR2E1 (0.67) | NR2E1HTR2AHTR2CHPGDHSD17B10 | |
| SCHEMBL29670383 | 0.74 | NR2E1 (1.00) | NR2E1HTR2AHTR2CHPGDHSD17B10 | |
| SCHEMBL21754250 | 0.74 | NR2E1 (0.67) | NR2E1HTR2AHTR2CHPGDHSD17B10 | |
| SCHEMBL700531 | 0.74 | NR2E1 (1.00) | NR2E1HTR2AHTR2CHPGDHSD17B10 | |
| SCHEMBL834930 | 0.74 | NR2E1 (1.00) | NR2E1HTR2AHTR2CHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382479-A | The fluoro- 3- hydroxyl propyl- 2- base ester derivative of carbamic acid 1,1,1- tri- as MAGL inhibitor | 辉瑞大药厂 | 2019-10-25 | — | — | CN | disclosed |
| CN-110234638-A | Heteroaryl phenoxy benzamide KAPPA opiates ligand | 辉瑞大药厂 | 2019-09-13 | — | — | CN | disclosed |
| CN-110198944-A | Heterocyclic ring spiroring compounds as monoacylglycerol lipase inhibitor | 辉瑞大药厂 | 2019-09-03 | — | — | CN | disclosed |
| CN-108884093-A | 6,7,8,9- tetrahydro -5H- pyrido [2,3-d] azepine * dopamine D 3 ligands | 辉瑞公司 | 2018-11-23 | — | — | CN | disclosed |