Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554440 | 0.88 | FFAR1 (0.56) | SMN1; SMN2FFAR1FFAR4KMT2AMEN1 | |
| SCHEMBL2918902 | 0.87 | FFAR1 (0.52) | SMN1; SMN2FFAR1FFAR4POLBALDH1A1 | |
| SCHEMBL2886228 | 0.85 | FFAR1 (0.62) | SMN1; SMN2FFAR1FFAR4POLBALDH1A1 | |
| SCHEMBL2925885 | 0.83 | FFAR1 (0.53) | FFAR1FFAR4POLBALDH1A1TDP1 | |
| SCHEMBL10078103 | 0.83 | FFAR1 (0.50) | SMN1; SMN2FFAR1FFAR4POLBALDH1A1 | |
| SCHEMBL2912655 | 0.83 | FFAR1 (0.54) | FFAR1FFAR4POLBALDH1A1TSHR | |
| SCHEMBL11595384 | 0.82 | NR1H4 (0.56) | SMN1; SMN2POLBALDH1A1TSHRKMT2A | |
| SCHEMBL22823845 | 0.81 | MAPK1 (0.62) | SMN1; SMN2FFAR1FFAR4POLBALDH1A1 | |
| SCHEMBL22823697 | 0.81 | FFAR1 (0.53) | SMN1; SMN2FFAR1FFAR4POLBALDH1A1 | |
| SCHEMBL14924837 | 0.80 | ALDH1A1 (0.54) | SMN1; SMN2POLBALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |