Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077240 | 0.82 | FFAR1 (0.52) | FFAR1ALDH1A1TSHRFFAR4 | |
| SCHEMBL31037707 | 0.81 | FFAR1 (0.51) | FFAR1ALDH1A1TSHRFFAR4POLB | |
| SCHEMBL7814760 | 0.81 | FFAR1 (0.51) | FFAR1ALDH1A1TSHRFFAR4POLB | |
| SCHEMBL2886658 | 0.81 | SMN1; SMN2 (0.56) | FFAR1ALDH1A1TSHRFFAR4POLB | |
| SCHEMBL2886228 | 0.79 | FFAR1 (0.62) | FFAR1ALDH1A1TSHRFFAR4POLB | |
| SCHEMBL22823696 | 0.79 | FFAR1 (0.41) | FFAR1ALDH1A1TSHRFFAR4POLB | |
| SCHEMBL21121314 | 0.79 | FFAR1 (0.67) | FFAR1 | |
| SCHEMBL21121315 | 0.79 | FFAR1 (0.67) | FFAR1 | |
| SCHEMBL22799987 | 0.79 | FFAR1 (0.67) | FFAR1 | |
| SCHEMBL18713516 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200399198-A1 | 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS | CELON PHARMA S.A. (PL) | 2020-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399198-A1 | 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS | GPR119, FFAR1, GPR65 | FFAR1 2/4885ALDH1A1 1839/4885TSHR 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.