Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 3/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.37 |
| ▸ | KDM6B | O15054 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75014 | 0.98 | THRB (0.55) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL22471964 | 0.96 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL30546666 | 0.96 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| Ammonia Solution, Strong SCHEMBL18139541 | 0.96 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL30546681 | 0.96 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL22471967 | 0.96 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| Succinic Acid SCHEMBL5426323 | 0.93 | THRB (0.61) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL2051132 | 0.90 | THRB (0.48) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL7090019 | 0.90 | THRB (0.58) | THRBTSHRPOLBAPEX1HTT | |
| Glycine SCHEMBL28311968 | 0.90 | THRB (0.48) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109041580-A | Film-like adhesive, sheet for semiconductor processing, and method for manufacturing semiconductor device | 琳得科株式会社 | 2018-12-18 | — | — | CN | disclosed |