SCHEMBL2051132

SCHEMBL2051132

C=C(C)C(=O)OCCC(=O)CCC(=O)CCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TSHR P16473 3/20 0.47
EGLN1 Q9GZT9 3/20 0.42
KDM6B O15054 2/20 0.42
KDM5C P41229 2/20 0.42
PHF8 Q9UPP1 2/20 0.42
KDM2A Q9Y2K7 2/20 0.42
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ACE P12821 1/20 0.39
LMNA P02545 2/20 0.38
SLC15A2 Q16348 1/20 0.38
ALDH1A1 P00352 4/20 0.38
GABRR1 P24046 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL28866675 0.90 THRB (0.53) THRBTSHREGLN1KDM6BKDM5C
SCHEMBL10426403 0.90 THRB (0.57) THRBTSHRPOLBAPEX1HTT
SCHEMBL13636032 0.89 TSHR (0.53) THRBTSHREGLN1KDM6BKDM5C
SCHEMBL75014 0.88 THRB (0.55) THRBTSHREGLN1KDM6BKDM5C
Succinic Acid SCHEMBL5426323 0.88 THRB (0.61) THRBTSHREGLN1KDM6BKDM5C
Ammonia Solution, Strong SCHEMBL18139541 0.86 THRB (0.53) THRBTSHREGLN1KDM6BKDM5C
SCHEMBL22471964 0.86 THRB (0.53) THRBTSHREGLN1KDM6BKDM5C
SCHEMBL22471967 0.86 THRB (0.53) THRBTSHREGLN1KDM6BKDM5C
SCHEMBL30546666 0.86 THRB (0.53) THRBTSHREGLN1KDM6BKDM5C
SCHEMBL30546681 0.86 THRB (0.53) THRBTSHREGLN1KDM6BKDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197810-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC. 2024-06-20 US disclosed
US-11819531-B2 Multifunctional zwitterionic polymer conjugates KODIAK SCIENCES INC. (US) 2023-11-21 US disclosed
EP-3659591-B1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2023-10-25 EP disclosed
US-20230277616-A9 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC. 2023-09-07 US disclosed
EP-3659591-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES Kodiak Sciences Inc. (US) 2020-06-03 EP disclosed
EP-3254678-B1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2020-02-19 EP disclosed
EP-2512462-B1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2017-08-23 EP disclosed
US-20160287715-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2016-10-06 US disclosed
US-20130045522-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2013-02-21 US disclosed
EP-2512462-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES Oligasis (US) 2012-10-24 EP disclosed
WO-2011075736-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2011-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230277616-A9 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 THRB 3455/4885TSHR 2714/4885EGLN1 4504/4885
US-20160287715-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 THRB 3455/4885TSHR 2714/4885EGLN1 4504/4885
US-20240197810-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 THRB 3455/4885TSHR 2714/4885EGLN1 4504/4885
US-11819531-B2 Multifunctional zwitterionic polymer conjugates PHOSPHO1, MSN, ZW10 THRB 3455/4885TSHR 2714/4885EGLN1 4504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.