Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867021 | 0.80 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL100857 | 0.77 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL31710459 | 0.75 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL99563 | 0.74 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL99694 | 0.74 | ALKBH1 (0.37) | DGAT1 | |
| SCHEMBL100637 | 0.74 | PRKCI (0.43) | DGAT1 | |
| SCHEMBL18440881 | 0.71 | HTR1A (0.36) | DGAT1 | |
| SCHEMBL99574 | 0.71 | CCNE1 (0.35) | DGAT1 | |
| SCHEMBL5134129 | 0.71 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL352030 | 0.71 | FGFR1 (0.35) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215861-B | Aromatic heterocycle substituted alkyne compound and preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-115215861-A | Aromatic heterocycle substituted alkyne compound and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-10-21 | — | — | CN | disclosed |