SCHEMBL28867306

SCHEMBL28867306

O=C(O[SiH2]c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
F2 P00734 1/20 0.54
TSHR P16473 5/20 0.50
TDP1 Q9NUW8 4/20 0.45
TP53 P04637 1/20 0.45
ALDH1A1 P00352 4/20 0.44
KMT2A Q03164 4/20 0.44
MAPT P10636 3/20 0.44
MAPK1 P28482 1/20 0.44
HIF1A Q16665 1/20 0.44
POLB P06746 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
PLA2G7 Q13093 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29184928 0.76 LMNA (0.56) LMNAF2TSHRTDP1TP53
SCHEMBL7052781 0.76 TSHR (0.58) LMNAF2TSHRTDP1TP53
SCHEMBL49492 0.76 ALDH1A1 (0.42) LMNAF2TSHRTDP1ALDH1A1
SCHEMBL1053847 0.71 ELANE (0.43) LMNATSHRTDP1TP53ALDH1A1
SCHEMBL4266491 0.71 CES1 (0.42) LMNAF2CES2CES1
Benzoyl Peroxide SCHEMBL9407293 0.71 LMNA (1.00) LMNAF2TSHRTDP1TP53
Benzoyl Peroxide SCHEMBL2929886 0.71 LMNA (1.00) LMNAF2TSHRTDP1TP53
SCHEMBL52413 0.71 LMNA (0.70) LMNAF2TSHRTDP1TP53
Benzoyl Peroxide SCHEMBL63 0.71 LMNA (1.00) LMNAF2TSHRTDP1TP53
Benzoyl Peroxide SCHEMBL5312311 0.71 LMNA (1.00) LMNAF2TSHRTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057881-A Organic catalytic synthesis method of chiral tetra-substituted silanal compounds and derivatization method thereof 贵州大学 2022-09-16 CN disclosed