SCHEMBL49492

SCHEMBL49492

CC(=O)O[SiH2]c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
HSD17B10 Q99714 3/20 0.39
TSHR P16473 3/20 0.39
NAPRT Q6XQN6 2/20 0.39
HPGD P15428 2/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
ELANE P08246 1/20 0.39
ESR1 P03372 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
HMGB1 P09429 1/20 0.39
GGT1 P19440 1/20 0.39
PTGS1 P23219 1/20 0.39
PTGS2 P35354 1/20 0.39
BLM P54132 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
MAPT P10636 2/20 0.37
HSP90AA1 P07900 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6972085 0.81 ALDH1A1 (0.31) ALDH1A1HSD17B10TSHRNAPRTHPGD
SCHEMBL10693762 0.77 HPGD (0.32) ALDH1A1HPGDKDM4EELANE
SCHEMBL29026463 0.77 ELANE (0.43) ALDH1A1TSHRKDM4EELANEESR1
SCHEMBL1053847 0.77 ELANE (0.43) ALDH1A1TSHRKDM4ETDP1ELANE
SCHEMBL28867306 0.76 LMNA (0.54) ALDH1A1HSD17B10TSHRNAPRTTDP1
SCHEMBL1053510 0.74 KMT2A (0.40) ALDH1A1HSD17B10TSHRHPGDKDM4E
Biphenyl SCHEMBL8168014 0.73 SMN1; SMN2 (0.50) ALDH1A1HSD17B10TSHRNAPRTHPGD
SCHEMBL4272675 0.72 CYP1A2 (0.38) ALDH1A1TSHRNAPRTHPGDKDM4E
SCHEMBL4266491 0.72 CES1 (0.42) CES2CES1LMNAF2
SCHEMBL707854 0.72 ALDH1A1 (0.38) ALDH1A1HSD17B10TSHRNAPRTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024063044-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM 日産化学株式会社 2024-03-28 WO disclosed
WO-2024019064-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING POLYFUNCTIONAL SULFONIC ACID 日産化学株式会社 2024-01-25 WO disclosed
WO-2024009993-A1 METHOD OF MANUFACTURING LAMINATE AND METHOD OF MANUFACTURING SEMICONDUCTOR ELEMENT 日産化学株式会社 2024-01-11 WO disclosed
WO-2023171733-A1 WAFER EDGE PROTECTIVE FILM-FORMING COMPOSITION FOR SEMICONDUCTOR MANUFACTURING 日産化学株式会社 2023-09-14 WO disclosed
WO-2023162968-A1 PHOTOCURABLE RESIN COMPOSITION CONTAINING SELF-CROSSLINKING POLYMER 日産化学株式会社 2023-08-31 WO disclosed
WO-2023157943-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM FORMING COMPOSITION HAVING UNSATURATED BOND AND CYCLIC STRUCTURE 日産化学株式会社 2023-08-24 WO disclosed
WO-2023136250-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM, AND SILICON-CONTAINING RESIST UNDERLAYER FILM 日産化学株式会社 2023-07-20 WO disclosed
WO-2023085414-A1 POLYCYCLIC AROMATIC HYDROCARBON-BASED PHOTO-CURABLE RESIN COMPOSITION 日産化学株式会社 2023-05-19 WO disclosed
WO-2023037979-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM, MULTILAYER BODY USING SAID COMPOSITION, AND METHOD FOR PRODUCING SEMICONDUCTOR ELEMENT 日産化学株式会社 2023-03-16 WO disclosed
WO-2023033094-A1 WAFER EDGE PROTECTIVE-FILM-FORMING COMPOSITION FOR SEMICONDUCTOR MANUFACTURING 日産化学株式会社 2023-03-09 WO disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-7604866-B2 Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance ASAHI KASEI KABUSHIKI KAISHA (JP) 2009-10-20 US disclosed
US-20090062460-A1 CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE HITACHI CHEMICAL CO., LTD. (JP) 2009-03-05 US disclosed
US-20090023855-A1 NOVEL CURABLE RESIN, PRODUCTION METHOD THEREOF, EPOXY RESIN COMPOSITION, AND ELECTRONIC DEVICE RESONAC CORPORATION (JP) 2009-01-22 US disclosed
CN-101124233-A Novel curable resin, method for producing same, epoxy resin composition and electronic component device HITACHI CHEMICAL CO LTD (JP) 2008-02-13 CN disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
US-20060269724-A1 Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance ASAHI KASEI KABUSHIKI KAISHA (JP) 2006-11-30 US disclosed
EP-1651581-A2 COATING SYSTEM FOR GLASS SURFACES, METHOD FOR THE PRODUCTION AND USE THEREOF Chemetall GmbH (DE) 2006-05-03 EP disclosed
WO-2004108846-A2 COATING SYSTEM FOR GLASS SURFACES, METHOD FOR THE PRODUCTION AND USE THEREOF CHEMETALL GMBH (DE) 2004-12-16 WO disclosed
US-5907008-A Black coloring composition, high heat resistance light-shielding component, array substrate, liquid crystal and method of manufacturing array substrate KABUSHIKI KAISHA TOSHIBA (JP) 1999-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062460-A1 CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, METHOD FOR PRODUCING CURING ACCELERATING COMPOUND-SILICA COMPOSITE MATERIAL, CURING ACCELERATOR, CURABLE RESIN COMPOSITION, AND ELECTRONIC COMPONENT DEVICE NCAPH, RAD51, H1-2 ALDH1A1 2071/4885HSD17B10 3185/4885TSHR 3490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.