SCHEMBL28867332

SCHEMBL28867332

Cc1cc(C#N)cc(C(=O)Cl)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.43
KMT2A Q03164 1/20 0.36
PKM P14618 1/20 0.35
MALT1 Q9UDY8 1/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
SLC2A1 P11166 2/20 0.33
SLC2A3 P11169 2/20 0.33
SLC2A4 P14672 2/20 0.33
SLC2A2 P11168 1/20 0.33
KCNH2 Q12809 4/20 0.33
GCK P35557 3/20 0.33
PPARG P37231 1/20 0.33
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
TYK2 P29597 1/20 0.33
JAK3 P52333 1/20 0.33
RIPK1 Q13546 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL950199 0.93 DHODH (0.42) DHODHKMT2APKMMALT1PDE4A
SCHEMBL24101462 0.93 DHODH (0.43) DHODHKMT2APKMMALT1PDE4A
SCHEMBL15271704 0.93 DHODH (0.43) DHODHKMT2APKMMALT1PDE4A
SCHEMBL20262070 0.92 DHODH (0.42) DHODHKMT2APKMMALT1PDE4A
SCHEMBL29377007 0.92 DHODH (0.42) DHODHKMT2APKMMALT1PDE4A
SCHEMBL959387 0.92 DHODH (0.42) DHODHKMT2APKMMALT1PDE4A
Cyantraniliprole SCHEMBL166640 0.92 DHODH (0.42) DHODHKMT2APKMMALT1PDE4A
SCHEMBL31059983 0.92 DHODH (0.42) DHODHKMT2APKMMALT1PDE4A
Cyantraniliprole SCHEMBL29354965 0.92 DHODH (0.42) DHODHKMT2APKMMALT1PDE4A
SCHEMBL15289892 0.91 DHODH (0.42) DHODHKMT2APKMMALT1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115057843-B Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2024-04-30 CN disclosed
CN-115057843-A Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2022-09-16 CN disclosed