SCHEMBL959387

SCHEMBL959387

Cc1cc(C#N)cc(C(N)=O)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.42
SLC2A1 P11166 6/20 0.37
SLC2A3 P11169 6/20 0.37
SLC2A4 P14672 6/20 0.37
SLC2A2 P11168 3/20 0.37
KMT2A Q03164 1/20 0.35
PKM P14618 1/20 0.35
MALT1 Q9UDY8 1/20 0.34
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34
NTRK1 P04629 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GCK P35557 2/20 0.33
KCNH2 Q12809 2/20 0.33
NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377007 1.00 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL31059983 1.00 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13442912 0.93 DHODH (0.37) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL950199 0.92 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL24101462 0.92 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL15271704 0.92 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL28867332 0.92 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
Cyantraniliprole SCHEMBL166640 0.91 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
Cyantraniliprole SCHEMBL29354965 0.91 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL20262070 0.91 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247647-B2 Cyano anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-24 US claimed
EP-3632911-B1 METHOD FOR PREPARING ISOXAZINONE COMPOUND AND APPLICATION THEREOF ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD (CN) 2023-08-09 EP disclosed
US-11299499-B2 Preparation method and application of isoxazinone compounds Zhejiang Zhuji United Chemicals Co., Ltd. (CN) 2022-04-12 US disclosed
EP-3632905-B1 METHOD FOR PREPARING N-ACYL ORTHO-AMINOBENZAMIDE MAX RUDONG CHEMICALS CO LTD (CN) 2021-12-01 EP disclosed
US-10807967-B2 Method of preparing N-acyl anthranilamide MAX (RUDONG) CHEMICALS CO., LTD. (CN) 2020-10-20 US disclosed
US-20200109152-A1 PREPARATION METHOD AND APPLICATION OF ISOXAZINONE COMPOUNDS Zhejiang Zhuji United Chemicals Co., Ltd. (CN) 2020-04-09 US disclosed
EP-3632905-A1 METHOD FOR PREPARING N-ACYL ORTHO-AMINOBENZAMIDE Max (Rudong) Chemicals Co., Ltd. (CN) 2020-04-08 EP disclosed
EP-3632911-A1 METHOD FOR PREPARING ISOXAZINONE COMPOUND AND APPLICATION THEREOF Zhejiang Zhuji United Chemicals Co., Ltd (CN) 2020-04-08 EP disclosed
US-20200087278-A1 METHOD OF PREPARING N-ACYL ANTHRANILAMIDE MAX (RUDONG) CHEMICALS CO., LTD. (CN) 2020-03-19 US disclosed
WO-2017174430-A1 COMBINATION OF NUCLEAR POLYHEDROSIS VIRUS AND DIAMIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-10-12 WO disclosed
US-7977278-B2 Suspension concentrates BAYER CROPSCIENCE AG (DE) 2011-07-12 US disclosed
US-7875634-B2 contain 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-pyrazole-5-carboxamide; for controlling invertebrate pests in both agronomic and nonagronomic environments E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-01-25 US disclosed
EP-2264022-A1 Cyano anthranilamide insecticides E. I. du Pont de Nemours and Company (US) 2010-12-22 EP disclosed
US-20100010051-A1 SUSPENSION CONCENTRATES BAYER CROPSCIENCE AG (DE) 2010-01-14 US disclosed
US-20090306147-A1 BIOLOGICAL EFFICACY OF AGROCHEMICAL COMPOSITIONS ON APPLICATION IN THE GROWTH SUBSTRATE SUITABLE FORMULATIONS AND USE THEREOF BAYER CROPSCIENCE AG (DE) 2009-12-10 US disclosed
US-20090275471-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2009-11-05 US disclosed
US-20070264299-A1 Cyano anthranilamide insecticides FMC CORPORATION 2007-11-15 US disclosed
US-7247647-B2 Cyano anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-24 US disclosed
WO-2007017433-A2 PESTICIDAL MIXTURES BASF SE (DE) 2007-02-15 WO disclosed
US-20060111403-A1 Cyano anthranilamide insecticides FMC CORPORATION 2006-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111403-A1 Cyano anthranilamide insecticides C1S, C5, CBR3 DHODH 1074/4885SLC2A1 4133/4885SLC2A3 3822/4885
US-20200087278-A1 METHOD OF PREPARING N-ACYL ANTHRANILAMIDE NAAA, PAM, HAAO DHODH 701/4885SLC2A1 3293/4885SLC2A3 3513/4885
US-11299499-B2 Preparation method and application of isoxazinone compounds NISCH, SI, DAO DHODH 240/4885SLC2A1 1717/4885SLC2A3 1451/4885
US-10807967-B2 Method of preparing N-acyl anthranilamide NAAA, PAM, HAAO DHODH 701/4885SLC2A1 3293/4885SLC2A3 3513/4885
US-20200109152-A1 PREPARATION METHOD AND APPLICATION OF ISOXAZINONE COMPOUNDS NISCH, SI, DAO DHODH 240/4885SLC2A1 1717/4885SLC2A3 1451/4885
US-20100010051-A1 SUSPENSION CONCENTRATES AKR7A2, CBR3, DCXR DHODH 510/4885SLC2A1 3684/4885SLC2A3 3546/4885
US-20090275471-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL PROPERTIES AADAC, ACHE, NAAA DHODH 1041/4885SLC2A1 4748/4885SLC2A3 4604/4885
US-20090306147-A1 BIOLOGICAL EFFICACY OF AGROCHEMICAL COMPOSITIONS ON APPLICATION IN THE GROWTH SUBSTRATE SUITABLE FORMULATIONS AND USE THEREOF CYP51A1, CYP21A2, CYP4X1 DHODH 933/4885SLC2A1 4237/4885SLC2A3 3348/4885
US-20070264299-A1 Cyano anthranilamide insecticides C1S, CBR3, C5 DHODH 1499/4885SLC2A1 4310/4885SLC2A3 4290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.