SCHEMBL31059983

SCHEMBL31059983

Cc1cc(C#N)cc(C(N)=O)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.42
SLC2A1 P11166 6/20 0.37
SLC2A3 P11169 6/20 0.37
SLC2A4 P14672 6/20 0.37
SLC2A2 P11168 3/20 0.37
KMT2A Q03164 1/20 0.35
PKM P14618 1/20 0.35
MALT1 Q9UDY8 1/20 0.34
PDE4A P27815 2/20 0.34
PDE4B Q07343 2/20 0.34
PDE4C Q08493 2/20 0.34
PDE4D Q08499 2/20 0.34
NTRK1 P04629 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GCK P35557 2/20 0.33
KCNH2 Q12809 2/20 0.33
NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29377007 1.00 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL959387 1.00 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL13442912 0.93 DHODH (0.37) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL950199 0.92 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL24101462 0.92 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL15271704 0.92 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL28867332 0.92 DHODH (0.43) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
Cyantraniliprole SCHEMBL166640 0.91 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
Cyantraniliprole SCHEMBL29354965 0.91 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2
SCHEMBL20262070 0.91 DHODH (0.42) DHODHSLC2A1SLC2A3SLC2A4SLC2A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 DHODH 90/4885SLC2A1 395/4885SLC2A3 825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.