Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28261949 | 0.89 | ALDH1A1 (0.46) | LMNAALDH1A1L3MBTL1MGLLMEN1 | |
| SCHEMBL28261984 | 0.89 | LMNA (0.39) | LMNAALDH1A1GAAL3MBTL1HCRTR1 | |
| SCHEMBL28261983 | 0.88 | LMNA (0.38) | LMNAALDH1A1HCRTR1HCRTR2MGLL | |
| SCHEMBL28263128 | 0.87 | KMT2A (0.42) | LMNAALDH1A1HCRTR1HCRTR2MEN1 | |
| SCHEMBL28263132 | 0.84 | ABCB1 (0.44) | EPHX2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL28263127 | 0.84 | LMNA (0.35) | LMNAEPHX2ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL28263133 | 0.79 | KMT2A (0.35) | HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL28261953 | 0.78 | KMT2A (0.36) | HCRTR2SIGMAR1MEN1KMT2A | |
| SCHEMBL28261971 | 0.78 | GRM5 (0.40) | LMNAEPHX2ALDH1A1L3MBTL1GRM5 | |
| SCHEMBL28263140 | 0.76 | KAT6A (0.39) | LMNAEPHX2ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071457-A | Inhibitors of indoleamine 2, 3-dioxygenase | 荷兰转化研究中心有限责任公司 | 2018-12-21 | — | — | CN | disclosed |