Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28263101 | 0.86 | HDAC4 (0.40) | ABCB1KMT2AMEN1RECQLL3MBTL1 | |
| SCHEMBL28261949 | 0.84 | ALDH1A1 (0.46) | KMT2AMEN1L3MBTL1GRM5ALDH1A1 | |
| SCHEMBL28867362 | 0.84 | LMNA (0.37) | KMT2AMEN1EPHX2L3MBTL1GRM5 | |
| SCHEMBL28263098 | 0.78 | KMT2A (0.36) | ABCB1KMT2AMEN1 | |
| SCHEMBL28263118 | 0.76 | HSD11B1 (0.41) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL28261985 | 0.76 | RORC (0.45) | KMT2AMEN1EPHX2ALDH1A1 | |
| SCHEMBL19328943 | 0.75 | MEN1 (0.47) | ABCB1ABCG2CNR2KMT2AMEN1 | |
| SCHEMBL28261986 | 0.74 | CCR5 (0.36) | KMT2AMEN1CCR5L3MBTL1ALDH1A1 | |
| SCHEMBL28261971 | 0.73 | GRM5 (0.40) | CCR5EPHX2L3MBTL1GRM5ALDH1A1 | |
| SCHEMBL28261984 | 0.72 | LMNA (0.39) | KMT2AMEN1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071457-A | Inhibitors of indoleamine 2, 3-dioxygenase | 荷兰转化研究中心有限责任公司 | 2018-12-21 | — | — | CN | disclosed |