Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4390654 | 0.78 | CYP3A4 (0.32) | KMT2APOLBHSD17B10HPGDACHE | |
| SCHEMBL9988198 | 0.77 | APOBEC3G (0.37) | ALDH1A1TSHRAPOBEC3GKMT2APOLB | |
| SCHEMBL8881481 | 0.75 | MCHR1 (0.43) | ALDH1A1TSHRKMT2AMEN1HPGD | |
| SCHEMBL8868904 | 0.75 | MEN1 (0.52) | ALDH1A1APOBEC3GKMT2APOLBMEN1 | |
| SCHEMBL1146257 | 0.74 | CHRM2 (0.48) | ALDH1A1TSHRAPOBEC3GKMT2AMEN1 | |
| SCHEMBL23734864 | 0.73 | MTNR1A (0.50) | ALDH1A1TSHRTP53KMT2APOLB | |
| SCHEMBL7086960 | 0.73 | APOBEC3G (0.58) | ALDH1A1TSHRAPOBEC3GKMT2APOLB | |
| SCHEMBL5250559 | 0.73 | SLC6A4 (0.42) | ALDH1A1TSHRAPOBEC3GKMT2ASLC6A4 | |
| SCHEMBL11857807 | 0.73 | PKM (0.38) | ALDH1A1TP53KMT2APOLBHSD17B10 | |
| SCHEMBL27632178 | 0.72 | KMT2A (0.59) | ALDH1A1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |