Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537055 | 0.87 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3APOBEC3GALDH1A1 | |
| SCHEMBL7086960 | 0.84 | APOBEC3G (0.58) | SLC6A4SLC6A2SLC6A3LMNAAPOBEC3G | |
| SCHEMBL11705626 | 0.81 | SLC6A4 (0.65) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 | |
| SCHEMBL587835 | 0.80 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3LMNAAPOBEC3G | |
| SCHEMBL1146257 | 0.80 | CHRM2 (0.48) | SLC6A4SLC6A2SLC6A3LMNAAPOBEC3G | |
| SCHEMBL11249347 | 0.80 | LMNA (0.47) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 | |
| SCHEMBL9988198 | 0.78 | APOBEC3G (0.37) | SLC6A4SLC6A2SLC6A3LMNAAPOBEC3G | |
| Hydrochloric Acid SCHEMBL8530226 | 0.78 | CYP2C9 (0.59) | SLC6A4SLC6A2SLC6A3LMNATSHR | |
| SCHEMBL11478443 | 0.77 | HTR1A (0.50) | SLC6A4SLC6A2SLC6A3KMT2ACHRNA7 | |
| SCHEMBL6299272 | 0.77 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3LMNAAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | claimed |
| CN-112533934-B | Polyoxometallate compounds exhibiting bright emissions and methods of making same | 纳米2D材料有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-112533934-A | Polyoxometallate compounds exhibiting bright emission and methods of making the same | 纳米2D材料有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-109824559-B | Method for synthesizing aryl-fluoro methylthio compound from Bunte salt | 南京理工大学 | 2021-03-02 | — | — | CN | disclosed |
| EP-1616859-B1 | Substituted cyclohexyl carboxylic acid compounds | SEIKAGAKU KOGYO CO LTD (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-1558252-B1 | SUBSTITUTED FURO [2,3-B]PYRIDINE DERIVATIVES | MERCK & CO INC (US) | 2007-10-10 | — | — | EP | disclosed |
| US-7091216-B2 | Substituted furo[2,3-b]pyridine derivatives | MERCK & CO., INC. (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1558252-A4 | SUBSTITUTED FURO 2,3-B| PYRIDINE DERIVATIVES | MERCK & CO INC (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1008592-B1 | Cyclic amide derivatives which inhibit cathepsin K | SEIKAGAKU KOGYO CO LTD (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1619189-A1 | N-(3-acyl-2-hydroxyalkyl) cycloalkyl amide derivatives | SEIKAGAKU CORPORATION (JP) | 2006-01-25 | — | — | EP | disclosed |
| WO-1989001488-A1 | RENIN INHIBITING PEPTIDES WITH NONPEPTIDE LINKAGES | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |
| EP-0287072-A2 | 2-Phenoxypyrimidine derivatives and herbicidal composition | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-10-19 | — | — | EP | disclosed |
| WO-1988001619-A1 | 1'-METHYL-BETA-LACTAM COMPOUNDS AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-03-10 | — | — | WO | disclosed |
| US-4621091-A | 5-LIPOXYGENASE INHIBITORS; USEFUL IN TREATMENT OF INFLAMMATION, PAIN AND FEVER | MERCK & CO., INC. (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0184844-A1 | 1-Methylcarbapenems having a 2-position substituent joined through an alkylenethio bridge | MERCK & CO. INC. (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0177927-A1 | 3-Hydroxybenzo[b]thiophene-2-sulfide derivatives as specific-5-lipoxygenase inhibitors | MERCK & CO. INC. (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4309428-A | Maytansinoids | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-01-05 | — | — | US | disclosed |
| EP-0025496-A1 | Maytansinoids, their production and therapeutic compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1981-03-25 | — | — | EP | disclosed |
| US-4139516-A | Process for the preparation of thianthrene compounds | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1979-02-13 | — | — | US | disclosed |