Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 17/20 | 0.45 |
| ▸ | EDNRB | P24530 | 15/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29932128 | 0.92 | P2RY1 (0.39) | EDNRAEDNRBHTR6MEN1TSHR | |
| SCHEMBL23536374 | 0.78 | EDNRA (0.42) | EDNRAEDNRBMEN1CYP2C9TSHR | |
| SCHEMBL23536530 | 0.74 | KIT (0.46) | EDNRAEDNRBHTR6 | |
| SCHEMBL29932046 | 0.72 | EDNRA (0.41) | EDNRAEDNRBMEN1KMT2A | |
| SCHEMBL28867443 | 0.71 | SCN9A (0.38) | HTR6 | |
| SCHEMBL29948618 | 0.71 | KMT2A (0.38) | EDNRAEDNRBMEN1CYP2C9TSHR | |
| SCHEMBL7221292 | 0.64 | EDNRA (0.71) | EDNRAEDNRBMEN1CYP2C9TSHR | |
| SCHEMBL29071636 | 0.63 | HTR2C (0.51) | HTR6 | |
| SCHEMBL7849896 | 0.63 | EDNRA (1.00) | EDNRAEDNRBMEN1CYP2C9TSHR | |
| SCHEMBL8479975 | 0.61 | EDNRA (0.66) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |