Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 8/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867414 | 0.92 | EDNRA (0.45) | HTR6EDNRAMEN1KMT2AEDNRB | |
| SCHEMBL23536374 | 0.77 | EDNRA (0.42) | EDNRAMEN1KMT2AEDNRBTSHR | |
| SCHEMBL23536530 | 0.73 | KIT (0.46) | HTR6EDNRAEDNRB | |
| SCHEMBL29948618 | 0.69 | KMT2A (0.38) | EDNRAMEN1KMT2AEDNRBTSHR | |
| SCHEMBL29932046 | 0.68 | EDNRA (0.41) | P2RY1EDNRAMEN1KMT2AEDNRB | |
| SCHEMBL28867443 | 0.66 | SCN9A (0.38) | HTR6 | |
| Trifluoroacetic Acid SCHEMBL31226949 | 0.64 | TSHR (0.36) | HTR6TSHR | |
| Trifluoroacetic Acid SCHEMBL16228956 | 0.61 | SIGMAR1 (0.51) | TSHR | |
| SCHEMBL7221292 | 0.61 | EDNRA (0.71) | EDNRAMEN1KMT2AEDNRBTSHR | |
| SCHEMBL8478606 | 0.61 | EDNRA (0.59) | P2RY1EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |