SCHEMBL2886746

SCHEMBL2886746

CCCc1cc(C)c(C)c(OC(=O)c2ccccc2)c1OC(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 0.46
PPARA Q07869 7/20 0.46
LMNA P02545 3/20 0.43
MAPT P10636 3/20 0.43
GAA P10253 2/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 6/20 0.42
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 2/20 0.39
PKM P14618 1/20 0.39
SREBF2 Q12772 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2502638 0.90 PPARG (0.45) PPARGPPARALMNAMAPTGAA
SCHEMBL2506210 0.90 MAPT (0.46) LMNAMAPTGAAPOLBKMT2A
SCHEMBL2508286 0.89 PPARG (0.46) PPARGPPARALMNAMAPTGAA
SCHEMBL2506231 0.89 PPARG (0.44) PPARGPPARALMNAMAPTGAA
SCHEMBL2507196 0.88 PPARG (0.47) PPARGPPARALMNAMAPTGAA
SCHEMBL2508822 0.86 PPARG (0.44) PPARGPPARALMNAMAPTGAA
SCHEMBL2505873 0.86 LMNA (0.43) PPARGPPARALMNAMAPTGAA
SCHEMBL2506145 0.85 PPARG (0.43) PPARGPPARALMNAMAPTGAA
SCHEMBL2480135 0.85 PPARG (0.43) PPARGPPARALMNAMAPTGAA
SCHEMBL2502312 0.85 PPARG (0.42) PPARGPPARALMNAMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8604235-B2 Production of substituted phenylene aromatic diesters and compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-10 US disclosed
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions W. R. GRACE & CO.-CONN. 2010-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions PAH, DDC, DDT PPARG 877/4885PPARA 398/4885LMNA 4145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.