Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28262838 | 0.84 | HPGD (0.50) | TSHRKMT2AMEN1HPGDMAPK1 | |
| SCHEMBL1863222 | 0.82 | ALDH1A1 (0.52) | TSHRKMT2AMEN1ALOX15HSD17B10 | |
| SCHEMBL970678 | 0.82 | MEN1 (0.46) | TSHRKMT2AMEN1ALOX15HSD17B10 | |
| SCHEMBL19268461 | 0.81 | SCD (0.53) | TSHRKMT2AMEN1HTTMAPT | |
| SCHEMBL4486676 | 0.81 | AGTR2 (0.52) | S1PR1CYP17A1 | |
| SCHEMBL19252949 | 0.80 | SCD (0.55) | TSHRKMT2AMEN1HTTMAPT | |
| SCHEMBL1985668 | 0.80 | MAPT (0.54) | KMT2AMEN1ALOX15HTTMAPT | |
| SCHEMBL29991279 | 0.80 | MAPT (0.54) | KMT2AMEN1ALOX15HTTMAPT | |
| SCHEMBL4476784 | 0.80 | BRD4 (0.51) | TSHRKMT2AMEN1LMNANPC1 | |
| SCHEMBL19278178 | 0.79 | SCD (0.52) | TSHRKMT2AMEN1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071542-A | CARBOXAMIDE DERIVATIVES USEFUL AS RSK INHIBITORS | 凤凰分子设计公司 | 2018-12-21 | — | — | CN | disclosed |