Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243927 | 0.78 | AMY1A (0.56) | AMY1AMAPTSMN1; SMN2KMT2AGAA | |
| SCHEMBL11243922 | 0.78 | AMY1A (0.56) | AMY1AMAPTSMN1; SMN2KMT2AGAA | |
| SCHEMBL24727973 | 0.70 | AMY1A (1.00) | AMY1AMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL31499008 | 0.68 | ALDH1A1 (0.73) | AMY1AMAPTSMN1; SMN2KMT2AGAA | |
| SCHEMBL28558439 | 0.68 | ALDH1A1 (0.73) | AMY1AMAPTSMN1; SMN2KMT2AGAA | |
| SCHEMBL28282172 | 0.65 | KMT2A (0.46) | AMY1AMAPTSMN1; SMN2KMT2AGAA | |
| SCHEMBL28238300 | 0.62 | ATM (0.44) | AMY1AMAPTSMN1; SMN2KMT2AGAA | |
| SCHEMBL28280836 | 0.61 | MEN1 (0.59) | MAPTSMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL28262982 | 0.61 | GAA (0.69) | AMY1AMAPTSMN1; SMN2KMT2AGAA | |
| SCHEMBL2318410 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053607-A | 4- (4- hydroxy phenyl methylene amino) -1,2,4- triazole -5- thioketones and its medical usage | 湖南大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-109053607-A | 4- (4- hydroxy phenyl methylene amino) -1,2,4- triazole -5- thioketones and its medical usage | 湖南大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-109053606-A | 4- (4- hydroxy phenyl methylene amino) -1,2,4- triazole -5- thioketones and its application | 湖南大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-109053606-A | 4- (4- hydroxy phenyl methylene amino) -1,2,4- triazole -5- thioketones and its application | 湖南大学 | 2018-12-21 | — | — | CN | disclosed |