SCHEMBL28868199

SCHEMBL28868199

FC(F)(F)OB(Oc1ccccc1)OC(F)(F)F.Fc1cccc(F)c1

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.37
TDO2 P48775 1/20 0.37
NFE2L2 Q16236 2/20 0.35
PPARG P37231 2/20 0.35
PPARA Q07869 1/20 0.35
PGR P06401 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CETP P11597 1/20 0.33
ATM Q13315 1/20 0.33
SLC6A4 P31645 1/20 0.33
KCNN4 O15554 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
ACHE P22303 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
NR4A2 P43354 1/20 0.31
MAOB P27338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4600384 0.87 TSHR (0.36) ALDH1A1
SCHEMBL28277261 0.77
Pyrrole SCHEMBL28230263 0.77 HDAC1 (0.32)
SCHEMBL28185685 0.74 PPARG (0.39) IDO1TDO2NFE2L2PPARGPPARA
SCHEMBL2163061 0.73 NFE2L2 (0.41) IDO1NFE2L2PPARGPPARASLC6A4
SCHEMBL29108105 0.72 TSHR (0.33) ALDH1A1
SCHEMBL4980059 0.68 CA1 (0.36) ALDH1A1
SCHEMBL29435934 0.67 GPR3 (0.50) NFE2L2CETP
SCHEMBL254534 0.67 GPR3 (0.50) NFE2L2CETP
SCHEMBL51246 0.67 LTA4H (0.50) KMT2AALDH1A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109196039-A Composition for thermoplastic elastomer, its manufacturing method and formed body 三井化学株式会社 2019-01-11 CN disclosed