Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | GRB2 | P62993 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3607848 | 0.92 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL3607843 | 0.92 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL28265941 | 0.90 | SLC6A4 (0.64) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL11158645 | 0.90 | SLC6A4 (0.64) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL27577124 | 0.85 | SLC6A4 (0.54) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| Hydrochloric Acid SCHEMBL27577123 | 0.85 | SLC6A4 (0.54) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL3788967 | 0.83 | SLC7A5 (0.55) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL1744966 | 0.83 | SLC7A5 (0.55) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL28567121 | 0.80 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL10888091 | 0.80 | SLC6A4 (0.51) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134481-B | Substituted pyrrole chromone compound or pharmaceutically acceptable salt thereof, and preparation method and application thereof | 中山大学 | 2021-05-14 | — | — | CN | disclosed |
| CN-109134481-A | A kind of substituted azole chromogen ketone compounds or its pharmaceutically acceptable salt and its preparation method and application | 中山大学 | 2019-01-04 | — | — | CN | disclosed |