Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FYN | P06241 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788967 | 1.00 | SLC7A5 (0.55) | SLC7A5PTGS1KDM4EPTGS2USP2 | |
| SCHEMBL3607848 | 0.91 | SLC6A4 (0.66) | SLC7A5PTGS1KDM4EPTGS2USP2 | |
| SCHEMBL3607843 | 0.91 | SLC6A4 (0.66) | SLC7A5PTGS1KDM4EPTGS2USP2 | |
| Hydrochloric Acid SCHEMBL11158645 | 0.89 | SLC6A4 (0.64) | SLC7A5PTGS1KDM4EPTGS2USP2 | |
| Hydrochloric Acid SCHEMBL28265941 | 0.89 | SLC6A4 (0.64) | SLC7A5PTGS1KDM4EPTGS2USP2 | |
| SCHEMBL31369822 | 0.88 | SLC7A5 (0.50) | SLC7A5PTGS1KDM4EPTGS2USP2 | |
| Phenylalanine Methyl Ester SCHEMBL7250904 | 0.85 | SLC7A5 (0.50) | SLC7A5PTGS1KDM4EHSD17B10PKM | |
| Trifluoroacetic Acid SCHEMBL28868211 | 0.83 | SLC6A4 (0.56) | SLC7A5PTGS1KDM4EPTGS2USP2 | |
| SCHEMBL3350932 | 0.83 | KDM6B (0.54) | PTGS1KDM4EPTGS2USP2ALOX15 | |
| SCHEMBL3359174 | 0.83 | KDM6B (0.54) | PTGS1KDM4EPTGS2USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232305-B1 | ANTICANCER AGENTS; BONE DISORDERS; ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM DISORDERS | NAEJA PHARMACEUTICAL INC. (CA) | 2001-05-15 | — | — | US | claimed |
| US-20230357307-A1 | CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING | ILLUMINA, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357307-A1 | CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING | ILLUMINA, INC. | 2023-11-09 | — | — | US | disclosed |
| EP-2387570-A1 | FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE | Amgen, Inc (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20110263647-A1 | FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2011-10-27 | — | — | US | disclosed |
| WO-2010091164-A1 | INHIBITORS OF GLUCOSYLCERAMIDE SYNTHASE | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010083246-A1 | FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263647-A1 | FLUOROISOQUINOLINE SUBSTITUTED THIAZOLE COMPOUNDS AND METHODS OF USE | TFEB, PCK2, JAK2 | SLC7A5 2232/4885PTGS1 402/4885KDM4E 3719/4885 |
| US-20230357307-A1 | CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING | TENT4A, TENT4B, DNTT | SLC7A5 1851/4885PTGS1 4767/4885KDM4E 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.